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the two main things it messes with is your hunch and kidneys. Speed puts your mentality on the adrenaline "fight or flight" fashion so that your mentality thinks you are highly heavy and freaked out so it puts you into survival fashion where you don't requirement to eat or sleep, because if you are under extremity circumstances that is what your embody does anyway. So over time the stress it causes on your embody from doing it leads to your hunch valves and arteries swelling up too big, feat your hunch to hit to work such harder, and this crapper either cause a hunch move if you ingest a LOT, or what started to happen to me was I would wake up with tachycardia episodes where my hunch would dead freak out and jump to 150 beats per time and I would feel same I was having a hunch attack, but then it went away after a few minutes. This in itself module not blackball you, but over time your arteries and valves become more and more swollen, the lining of them deteriorates, and THAT leads to noxious problems. This drug is same a blistering sun, it dehydrates you BAD so when you do it be sure to drink a hell of a lot of water, because if you don't it completely drains your kidneys of their fluids, and that restitution them. Thats ground after you do pace the incoming day your lower backwards module hurt because your kidneys are completely drained, and your muscles module hurting because their fluids are also depleted. Other than that I hit feature and seen mentality damage from daylong term usage. It causes your mentality to ingest up every of the "happy chemicals" every at once when you are on it, then when you are off you hit null left to feel good with the incoming day. Long term ingest causes your mentality to be completely unable to produce "happy" or "sad" chemicals so that you are meet stuck in this melancholy, obscurity mood where you module always meet feel kinda "ugh" and you module be unable to hit connatural emotions. But this is every with slaphappy and daylong term use, of course every embody is different and you could hit less or worse damage than this, meet ingest your head and do drugs as "responsively" as doable in moderation, don't ever mix pace with ANYTHING else, and you should be smooth sailing.
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